Archive for March 2013

Study Suggests Caffeine and Exercise May Be Protective Against Skin Cancer

March 8, 2013
 
Coffee pouring
The combined effects of exercise plus caffeine consumption may be able to ward off skin cancer and also prevent inflammation related conditions including obesity-linked cancers.
“We found that this combination treatment can decrease sunlight-caused skin cancer formation in a mouse model,” said Yao-Ping Lu, Ph.D., associate research professor of chemical biology and director of skin cancer prevention at the Rutgers Ernest Mario School of Pharmacy in Piscataway, N.J. He presented these findings at the American Association for Cancer Research  Annual Meeting held in Chicago.
“I believe we may extrapolate these findings to humans and anticipate that we would benefit from these basic combination treatments as well,” Dr. Lu added.
The researchers evaluated the effects of caffeine and exercise on laboratory mice at high risk for developing skin cancer. Results showed that mice that took a dose of caffeine and exercised with a running wheel experienced 62 percent fewer skin tumors. The volume of tumors also decreased by 85 percent compared with the mice that did not consume caffeine or exercise.
Positive effects were also found with either caffeine or exercise alone, but to a lesser degree. Interestingly, he researchers observed a 27 percent reduction in tumors in the caffeine-only mice and a 61 percent reduction in tumor size. In the exercise-only mice, researchers discovered that tumor activity decreased by 35% and tumor volume decreased by 70%.  fitness woman at Gym
The researchers also found that exercise and caffeine reduced weight and inflammation. They fed mice a high-fat diet of omega-6 fatty acid-rich foods and measured the volume of the parametrial fat pad (the largest fat area in a mouse) after two weeks of exercise and/or caffeine treatment.
Mice that had caffeine and exercised had a fat  weight decrease of 63%. Caffeine-only mice had a 30% decrease, and exercise-only mice had a 56% decrease. The development and size of cancer decreased as well. Researchers believe the correlation is inflammation, which dropped as much as 92% in mice that exercised and consumed caffeine.

Reference:

American Association for Cancer Research

(AACR – 2012, April 3). Caffeine and exercise may be protective against skin cancer caused by sun exposure, study suggests.

This article is for informational and educational
purposes only;  It is not intended to provide
medical advice, diagnosis or treatment.
Consult your doctor or healthcare professional.
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Here’s Why Cruciferous
Vegetables May Improve
Breast Cancer Survival!

  

more cruciferous veggies
A study by Vanderbilt-Ingram Cancer Center and Shanghai Center for Disease Control and Prevention investigators reveals that breast cancer survivors who eat more cruciferous vegetables including broccoli, spinach and kale, as well as cabbage and cauliflower may have improved survival.

The study was presented at the American Association for Cancer Research
Annual Meeting in Chicago, Ill.

Breast cancer survivors should follow the accepted nutritional guidelines of eating vegetables daily and specifically increase intake of cruciferous vegetables including: broccoli greens, cabbage and cauliflower as part of a total healthy dietary regimen.
Researchers investigated the role of cruciferous vegetables in breast cancer survival among women in the Shanghai Breast Cancer Survival Study, a prospective study of 4,886 Chinese breast cancer survivors who were diagnosed with stage 1 to stage 4 breast cancer from the period 2002 to 2006.
After adjusting for lifestyle factors, demographics and clinical characteristics, the researchers determined cruciferous vegetable intake during the first 36 months after breast cancer diagnosis was associated with a reduced risk for total mortality, specific breast cancer mortality and recurrence of the disease. Survival rates were influenced by vegetable consumption. Women who regularly ate more of these vegetables, their risk of death or cancer recurrence decreased.
Women who were in the highest quartiles of intake of vegetables per day had a 62 percent reduced risk of total mortality, 62 percent reduced risk of breast cancer mortality, and 35 percent reduced risk of breast cancer recurrence, compared to women with the lowest quartile of intake.

Cruciferous vegetable consumption habits
differ between China and the United States;
The amount of dietary intake of these vegetables among Chinese women is much higher than that of U.S. women.

The most commonly consumed cruciferous vegetables in China include turnips, Chinese cabbage (bok choy) and greens; In the United States and other Western countries, broccoli and Brussels sprouts are the most commonly consumed cruciferous vegetables.
The key nutritional advantage of cruciferous vegetables is they contain powerful protective phytochemicals known as isothiocyanates and indoles; these appear have the beneficial protective effect against some types of cancer. The levels of these bioactive compounds, which play a key role in the anticancer effects of cruciferous vegetables, depends on the amount and type of cruciferous vegetables regularly consumed.
Future studies will measure the bioactive isothio-cyanate and indole compounds in these vegetables and the host factors that may influence their protective effects to improve the understanding of the association between cruciferous vegetable consumption and breast cancer outcomes. cruciferous veggies

Reference:
Vanderbilt University Medical Center
(2012, April 3)  “Eating cruciferous
vegetables may improve breast cancer survival.”
 This article is for informational and educational
purposes only;  It is not intended to provide
medical advice, diagnosis or treatment.
Consult your doctor or healthcare professional.